Deals June 11: Sony W650 16MP Camera Bundle $119.99 FS

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The New MacBook Air: Faster and Still Super Skinny [MacBook Air]

Today's lovely debutante is the 2012 Pro, of course, but the Air—who we suspect gave the Pro some serious body image problems over the years—is getting a promotion too. Ivy Bridge, USB 3.0, and speed, speed, speed. More »

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More Progress Made on Artificial Pancreas for Diabetes Patients

SUNDAY, June 10 (HealthDay News) -- Progress continues to be made on the development of an artificial pancreas, a device that would ease the burden of living with type 1 diabetes.

Several artificial pancreas research groups presented their latest findings Saturday at the American Diabetes Association annual meeting in Philadelphia, and the hope is that the makers of one or more of the devices will be seeking regulatory approval within the next five years.

"I'm cautiously optimistic," said Aaron Kowalski, assistant vice president for treatment therapies at the Juvenile Diabetes Research Foundation. "The FDA has really turned the corner and is moving much faster.... My hope is that in the next year or two, we'll see approvals on devices that can minimize [low blood sugar levels], and that's just the tip of the iceberg."

Type 1 diabetes is an autoimmune disease in which the body's immune system turns against healthy cells. In type 1 diabetes, the immune system attacks beta cells in the pancreas, effectively destroying the body's ability to produce the hormone insulin. Insulin helps metabolize carbohydrates from food and fuels the body's cells.

Type 1 diabetes can be managed with insulin injections or a pump that delivers insulin via a tiny catheter inserted under the skin every few days. The problem with both insulin-delivery techniques is that people have to estimate how much insulin they'll need based on the foods they eat and how much activity they will be doing.

Too much insulin can result in low blood sugar levels (hypoglycemia), which, in turn, can cause a person to pass out. Low blood sugar levels can even lead to death. Too little insulin leads to high blood sugar levels (hyperglycemia), which over time can cause serious complications, such as heart disease and kidney and eye problems.

An artificial pancreas, which sometimes is referred to as a closed-loop system because it doesn't require user input, could potentially solve those problems by taking over the decision-making process and applying sophisticated computer algorithms to decide how much insulin is needed at any given moment.

But developing such a device isn't as easy as it sounds.

First, the device has to be able to continuously detect patients' blood sugar levels and know whether the levels are trending up or down. There has to be a piece of the device that holds and delivers insulin. And there needs to be a way to deal with low blood sugar levels.

Someone with type 1 diabetes typically consumes food or a sugar-containing drink to counteract drops in blood sugar. Some devices will shut off and sound an alarm to alert the person to treat their low blood sugar.

At least one device in development contains not only insulin, but also a hormone called glucagon that can quickly raise blood sugar levels.

Researchers at Boston University, Harvard Medical School and Massachusetts General Hospital are developing the device. In addition to reporting on the latest in-hospital trials of their device, they presented a prototype that uses a continuous glucose monitor, an insulin pump that also will house the artificial pancreas software with a low-powered Bluetooth device, and an app designed for the iPhone 4S, said Edward Damiano, one of the device's developers.

"It's a totally pocket-sized device," said Damiano, associate professor of biomedical engineering at Boston University. Damiano, who will be wearing his team's version of the artificial pancreas for the presentation, said their device is the only one that truly is closed-loop because it includes both glucagon and insulin, allowing it to respond to both high and low blood sugar levels without user input.

Damiano said they soon will be filing paperwork for five-day in-hospital trials of their system. They also are planning two transitional studies for summer 2013 that will include campers at a diabetes camp and hospital personnel with type 1 diabetes. If all goes well, their hope is that they will be able to do a large-scale six-month outpatient trial by 2015, Damiano said.

Another research group, at the University of Virginia School of Medicine, is recruiting people for outpatient trials on an artificial pancreas device similar to the one Damiano's team is working on. Although this device also uses a smartphone to display the device's information, however, it contains only insulin, not glucagon.

Another device, called a Hypoglycemia-Hyperglycemia Minimizer, which was developed in a partnership with the Juvenile Diabetes Research Foundation and the insulin-pump maker Animas, was able to automatically predict increases and decreases in blood sugar levels. It also was able to change insulin delivery accordingly in a study that included 13 people between 24 and 57 years old with type 1 diabetes.

"The successful completion of this study using the [Hypoglycemia-Hyperglycemia Minimizer] system in a human clinical trial is a significant step forward in the development of an advanced first-generation artificial pancreas," Dr. Henry Anhalt, chief medical officer for Animas, said in a statement.

Kowalski is optimistic about the future development of an artificial pancreas.

"This gives me a lot of hope that we're really starting to roll to what could be full-blown product development," he said.

Kowalski said he believes the artificial pancreas likely will be approved in steps. "I don't think it will be one product, but an evolution," he said.

First, he said, will be a device designed to minimize the impact of severe low blood sugar. After that, it's likely that there will be a device to prevent low blood sugar from occurring in the first place.

"Each of these steps should be meaningful, make life easier and improve glucose control for people with type 1 diabetes," Kowalski said.

More information

Learn more about the artificial pancreas from the U.S. Food and Drug Administration.

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Gomez gives Germany 1-0 win vs. Portugal

By NESHA STARCEVIC

AP Sports Writer

Associated Press Sports

updated 5:40 p.m. ET June 9, 2012

LVIV, Ukraine (AP) -Moments before he was supposed to be taken off, Mario Gomez headed in the winning goal for Germany.

The Bayern Munich striker made a surprise start Saturday against Portugal at the European Championship and knocked in a deflected cross from Sami Khedira in the 72nd minute to give the Germans a 1-0 victory in Group B.

Gomez, who had created little before the goal, was due to be replaced by Miroslav Klose, who was already waiting on the touchline on his 34th birthday.

Gomez nearly got another goal before Klose finally came on in 80th.

Germany was the better team but found it hard to break down a defensive Portugal. The Germans, seeking their first title since 1996, are considered one of the favorites of the tournament despite being in the toughest group along with the Netherlands and Denmark.

Although Cristiano Ronaldo did little until late in the match, Portugal had a chance to equalize in the 84th when Nani hit the crossbar with a misdirected cross - the second time the team struck the frame in the match. And Silvestre Varela had another opportunity in the 89th but he shot straight at Germany goalkeeper Manuel Neuer from close range.

Although Germany monopolized possession and chances, Pepe had the best opportunity of the first half, hitting the underside of the German crossbar late in the period after a Portugal corner. The ball hit the line and bounced out.

Despite indicating before the match that he would start the veteran Klose as striker, coach Joachim Loew went with Gomez. In another move against expectations, Loew also picked Mats Hummels as his starting center back in place of Per Mertesacker. Both Mertesacker and Klose came into the tournament after long-term injuries.

Boateng played at right back although Loew had been upset about newspaper stories about his private life.

In the end, Loew's decisions proved right. Hummels had a good game, Boateng dealt reasonably well with Ronaldo and Gomez scored the decisive goal.

---

Lineups:

Germany: Manuel Neuer; Jerome Boateng, Mats Hummels, Holger Badstuber, Philipp Lahm, Sami Khedira, Bastian Schweinsteiger, Thomas Mueller (Lars Bender, 90), Mesut Oezil (Toni Kroos, 87), Lukas Podolski, Mario Gomez (Miroslav Klose, 80).

Portugal: Rui Patricio; Joao Pereira, Bruno Alves, Pepe, Fabio Coentrao; Joao Moutinho, Miguel Veloso, Raul Meireles (Silvestre Varela, 80); Cristiano Ronaldo, Helder Postiga (Nelson Oliveira, 70), Nani.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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More newsAnne-Christine Poujoulat / AFP - Getty Images

Germany's win hardly delightful

PST: The Germans did what they needed to in 1-0 win over Portugal, but their inability to break down the defense might be a concern.

Gomez gives Germany 1-0 win vs. Portugal

LVIV, Ukraine (AP) -Mario Gomez made a surprise start and headed in the lone goal for Germany on Saturday in a 1-0 victory over Portugal in Group B of the European Championship.

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NHK lays out Olympic broadcast plans, Super Hi-Vision test viewing locations in Japan

We've already run down Olympic broadcast plans in the US and UK, and now Japanese broadcaster NHK has unveiled some information. Similar to the others there is not only the TV production including data about ongoing competition, but also an online component complete with live video access on mobile devices, but also support for the acTVila video on-demand portal. The other notable information is that it's locked down locations and details for those trial Super Hi-Vision broadcasts, listing four spots where people can get their eyes on some sweet 8K UHDTV action. While most of them will be displayed by projectors, including a 520-inch screen in Shibuya, while Akihabara's Studio Park will feature a 360-inch LCD. The details for UK and US are a bit more vague, but if we have to track where in Washington D.C. NBC is letting the 33MP resolution video and 22.2ch sound out for a trial just by its scent, then that's what we'll have to do.

NHK lays out Olympic broadcast plans, Super Hi-Vision test viewing locations in Japan originally appeared on Engadget on Sat, 09 Jun 2012 04:37:00 EDT. Please see our terms for use of feeds.

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50th anniversary Texas Water Safari Saturday

The precursor to the Texas Water Safari was a 370-mile, month-long float in 1962 from San Marcos to Corpus Christi by a self-described country boy and an employee of the San Marcos Chamber of Commerce.

?It was a publicity stunt,? said Bill ?Big Willie' George, the country boy who provided most of the food for the journey with a .410 shotgun and fishing lures he kept in his hat.

George had no idea what he was starting, but his partner, Frank Brown, had a vision of a race.

On Saturday, more than 130 boats will the mark the 50th anniversary of that float by racing a 260-mile course to Seadrift, starting in the same spring-fed lake George and Brown did.

The boats have changed from George's 12-foot aluminum Lone Star skiff. Most are now custom canoes of Kevlar and carbon fiber.

The fastest teams will paddle nonstop for two days, and their food will consist of powdered carbohydrates and protein. A shotgun is simply too much weight.

While the style is different, the spirit of the race and what it does to those who complete are not.

?There are no losers in the race,? George said. ?You are down on the river with a paddle in your hand, and it looks like a person has never been there before. It is a hell of an experience.?

While George hunted squirrels and fished, Brown was promoting the adventure to the press.

?We made a hell of a team,? George said. ?I knew how to keep it floating, and he knew how to keep talking.?

In 1963, Brown organized the Texas Water Safari and billed it as ?the toughest boat race in the world.?

In the race brochure, he told competitors ?this event has been deliberately designed to test to the utmost your physical endurance, ingenuity, seamanship and will to win.?

Of the 57 boats that started, two reached Corpus Christi, and Brown landed a six-page photo spread in Life magazine documenting the 12-day race.

Although Brown has died, racers have shown up in San Marcos every June for the safari he started.

Over the years, the course was shortened, with the finish line moving from Corpus Christi to Freeport, and then Port Lavaca, and, in 1971, to Seadrift.

Rodger Zimmerman was the third boat in the Safari on that first race to Corpus Christi.

?I got the farthest of anyone who did not finish,? he said.

Having run out of food in Victoria after paddling 200 miles, he survived on a subsistence diet ? the race rules then and now do not allow any resupply. He managed to get to the saltwater but could not get his 10-foot canvas kayak to cut through the swells.

?I was so disgusted with myself I said I would never go again,? Zimmerman said.

But in 1994 he was back and won the novice division with a partner. The next year he went solo. This year he will watch the race and assist a team captain, handing out water from the side of the race course.

It is the only assistance allowed.

Next year, when he turns 76, his goal is to be the oldest person ever to finish the Safari.

?I think the river is addictive,? said Tom Goynes, who was a fixture in the race for years and is now supporting his daughter, Sandy Yonley, 30, who will be doing the race for the 11th time. ?You get to where you just enjoy seeing the river like an old friend year after year.?

And the racers get to know the river intimately.

John Bugge, 61, has completed 33 of the 35 safaris he has entered, more races than anyone. He has won almost every class from unlimited to solo to parent/child multiple times.

?It's the hardest and worst thing that happens to me every year,? he said.

Like Zimmerman, he has lost all his food. He also has had partners quit and felt his back tighten up to where he could hardly pull a stroke while sitting up.

He delights in dealing with the challenges. He sees it as preparation for any other difficulty he may face in life.

?It comes down to how you handle it,? he said of the race and of life.

He reminds those who will take his advice the pain and anguish from paddling for 24 hours can only get so bad. That quitting is easy and if you keep going you may actually start to feel better.

This year, Bugge is racing with Bob Vincent of Dorchester, Ontario, who at 69 has raced in Austria and England. He has built rafts and raced them down the Amazon and won a 460-mile race on the Yukon.

He agrees with the race promoters that the safari is the toughest.

Not only is the paddling nonstop ? for those who want to win ? but the logistics, June Texas heat, insects and the nature of the course bring a set of challenges that no other race has.

?In other races you portage around the dams,? he said. ?In the safari you go right over them. It's scary as hell going over the dams.?

But he keeps coming back.

The next generation of paddlers is following the same pattern.

Last year Courtney Weber, 21, was the youngest woman to finish the safari in a solo canoe.

This year she will go with her younger sister, Cayla. He mother, Myla Weber, and father, Jim Weber, are each going in solo canoes.

For the Weber family, a year is not complete without participating in the Safari, Courtney explained.

?I definitely feel like there is nothing I can't do because I did the safari solo,? she said.

Next year she will start in Baylor's doctoral statistics program.

For George, taking a boat from San Marcos to Corpus Christi was one of the crowning moments of his life.

?But you ain't got money enough to get me to do it again,? he said.

Instead, he prefers to watch the racers. Once across the finish line, they join a unique club, and he welcomes them in.

cmcdonald@express-news.net

Colin McDonald will participate in the Texas Water Safari this weekend.

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Mariners 6-pack combines for no-hitter vs. Dodgers

SEATTLE (AP) ? Mariners catcher Jesus Montero ran around with his arms in the air looking for someone to join in the party.

After the final out of an odd no-hitter pitched by Kevin Millwood and five Seattle relievers, nobody was quite sure how to celebrate.

"I think we all took a second and looked around and were like, did that really happen ? and what do we do now?" shortstop Brendan Ryan said.

Yes, the Mariners pitched the fourth no-hitter of the major league season Friday night and by far the most unconventional.

Millwood left after six innings with a groin injury and a stream of Seattle relievers continued to hold the Dodgers in check until Tom Wilhelmsen closed out a 1-0 win over Los Angeles for his third save.

Seattle's six-pack of arms joined the Mets' Johan Santana, the Angels' Jered Weaver and White Sox right-hander Philip Humber on the no-hit list of 2012. It was the second no-hitter at Safeco Field this season after Humber's perfect game against the Mariners in April ? the first two in the park's 13-year history.

The six pitchers tied the record for the most used in a no-hitter and each played an important role, from Charlie Furbush quickly entering the game after Millwood left in the seventh to Brandon League finding the nasty splitter that had eluded him in recent weeks to Wilhelmsen being so oblivious that teammates had to tell him he just completed a no-hitter.

"He was surprised," Montero said. "He didn't know. ... I jumped on him and I was like, 'Hey, it's a no-hitter!' And he went, 'What?!" And then he was so happy after that. He was so focused on the game. That's what happened."

It was less than two months ago that the Mariners were standing stunned while Humber and the White Sox celebrated on the Safeco Field mound. This time, it was the Mariners' turn to bounce around.

Exactly a week after Santana pitched the first no-hitter in Mets history, Millwood cruised through six innings, giving up only a walk. But after throwing his first warmup pitch for the seventh he felt a twinge in his groin and was pulled.

Seattle's bullpen finished the no-hitter when Wilhelmsen retired Andre Ethier on a routine grounder to second base that ended a 1-2-3 ninth inning.

The Dodgers nearly got a hit when speedy Dee Gordon led off the ninth with a slow roller to shortstop. Ryan, who had just entered as a defensive replacement, charged in and fired to first, where umpire Ted Barrett called Gordon out on a bang-bang play.

Gordon and manager Don Mattingly argued. Replays were inconclusive.

Elian Herrera then lined out to Ryan before Ethier's grounder ended the first no-hitter for the Mariners since Chris Bosio shut down Boston on April 22, 1993. Seattle's other no-hitter was thrown by Randy Johnson against Detroit on June 2, 1990.

It was the 10th combined no-hitter in big league history and the first since six Astros accomplished the feat at Yankee Stadium on June 11, 2003. Roy Oswalt started that game for Houston but left two pitches into the second inning with a strained right groin.

"I'm excited for all these guys that came in the game out of the bullpen and kept it going. It's a little bit more exciting for those guys when they can be a part of it," Millwood said.

The 37-year-old Millwood, who spent much of last season in the minors, threw a no-hitter all his own for the Philadelphia Phillies against San Francisco on April 27, 2003. And this combined no-hitter was no ordinary feat: The Dodgers entered with the best record in the majors and the second-highest batting average in the National League.

"This was a lot better than having it against you, that's for sure," said Seager, whose brother Corey was selected by the Dodgers in the first round of Monday's amateur draft.

Millwood pulled himself out after throwing one warmup pitch before the seventh. It was later announced he had a mild right groin strain. He said he first felt it on the next-to-last pitch of the sixth.

Millwood struck out six and threw 68 of Seattle's 114 pitches.

Furbush took over and retired Gordon to start the seventh, but committed a two-base throwing error on Herrera's grounder, giving the Dodgers their first scoring chance. Furbush struck out Ethier, and manager Eric Wedge went to hard-throwing rookie Stephen Pryor (1-0) to face Juan Rivera.

Rivera went down on strikes but Pryor started the eighth by walking Bobby Abreu and Jerry Hairston Jr. on nine pitches. Lucas Luetge was next in line and got the first out of the inning on James Loney's sacrifice bunt.

That brought up A.J. Ellis and Seattle turned to League, recently demoted from the closer role. League got Ellis to hit a sinking liner to left and defensive replacement Chone Figgins made a running catch. His strong throw home kept pinch-runner Alex Castellanos at third base.

League then struck out Tony Gwynn Jr. to end the inning.

"Really, I had visions of winning that game without a hit," Mattingly said. "First and second, I'm thinking wild pitch, sac fly. With League in the game, that split, you never know."

The previous no-hitter against the Dodgers was thrown by Atlanta's Kent Mercker on April 8, 1994. Weaver and Jose Arredondo combined to hold the Dodgers hitless for eight innings in a 1-0 Dodgers win in 2008, but that game doesn't count as a no-hitter under the rules baseball adopted in 1991 because the Angels only had to pitch eight innings.

Seattle's run came in the seventh inning thanks to a two-out rally started by Suzuki's infield single. He stole second, Dustin Ackley walked and Seager came through with his 23rd two-out RBI of the season. His line-drive single off reliever Scott Elbert (0-1) glanced off the glove of a leaping Gordon at shortstop and dropped in left field.

Millwood also took a no-hitter into the sixth inning May 18 at Colorado and finished with a two-hitter. He retired his first 12 batters Friday before a leadoff walk to Rivera in the fifth.

The closest the Dodgers came to a hit off Millwood was Gordon's bunt leading off the fourth. Seager ran in from third for a fine barehanded pickup and threw out Gordon by a half-step.

"When you win a 1-0 ballgame in that fashion, so many different people have to step up, defensively and on the mound," Wedge said. "That's what you saw tonight."

NOTES: Seattle ace Felix Hernandez was pushed back and will start Tuesday against San Diego. Hernandez has been bothered by a sore back. ... It was the Dodgers' fourth game in Seattle and first since 2000. ... It was Pryor's first major league win.

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